Sinus node inhibitors

Drug class: Sinus node inhibitors

Generic (Brand) names: ivabradine (Corlanor)

In heart failure, the weakened heart canít pump enough oxygen- and nutrient-rich blood throughout the body.

Sinus node inhibitors slow the heart rate so the heart can pump more blood through the body each time it beats.

You may be prescribed this drug if you continue to have symptoms despite taking other heart failure medications.

Sinus node inhibitors improve symptoms, reduce hospitalizations, and can help you live longer.

Side effects may include:

  • Heart rate that is too slow
  • High blood pressure
  • Atrial fibrillation, a condition that can cause an irregular heart rhythm
  • Vision disturbance

Your provider will have told you what dose of this medication to take, and how many times per day to take it. The label on your medication bottle should also indicate how many pills to take, and how often.

Over time, your provider may adjust your dose.

Make sure the dose you need to take matches the strength of the tablets in your bottle. If the strength of your tablet does not match the dose you have been prescribed, you may need to split the pill and have only part of it, or take more than one pill. Always remember to consult your provider if you are unclear about what your most recent dose of ivabradine is.

This medication is usually taken twice a day with food.

Tell your provider if you experience side effects from this medication. He or she may be able to adjust your dose or switch you to a different drug.

This drug can cause your heart rate to drop too low, particularly if you are also taking a beta blocker. Your provider will make sure you have the minimum required resting heart rate before prescribing this drug. If you develop palpitations or an irregular heart beat while on this drug, notify your provider immediately.

You will need a baseline electrocardiogram (ECG) prior to starting ivabradine.

Your provider may ask you to monitor your heart rate at home to make sure it is not too low.

You may not feel different in the short term if you do not take this medication as directed. Over time, however, you will feel worse and be at greater risk for hospitalization. Your heart failure will also continue to progress.